HMM Summary Page: TIGR03769

Functionactinobacterial surface-anchored protein domain
Trusted Cutoff30.90
Domain Trusted Cutoff30.90
Noise Cutoff23.35
Domain Noise Cutoff23.35
Isology Typedomain
HMM Length41
AuthorHaft DH
Entry DateJun 14 2009 11:59PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes a repeat domain that one to three times in Actinobacterial proteins, some of which have LPXTG-type sortase recognition motifs for covalent attachment to the Gram-positive cell wall. Where it occurs with duplication in an LPXTG-anchored protein, it tends to be adjacent to the substrate-binding protein of the gene trio of an ABC transporter system, where that substrate-binding protein has a single copy of this same domain. This arrangement suggests a substrate-binding relay system, with the LPXTG protein acting as a substrate receptor.
Genome PropertyGenProp0857: anchored repeat-class ABC transporter, P. acnes type (HMM)