HMM Summary Page: TIGR03795

Functionribosomal natural product, two-chain TOMM family
Trusted Cutoff41.00
Domain Trusted Cutoff41.00
Noise Cutoff34.55
Domain Noise Cutoff34.55
Isology Typesubfamily
HMM Length114
AuthorHaft DH
Entry DateJul 24 2009 1:52PM
Last ModifiedMar 13 2012 3:09PM
CommentMembers of this protein family are found sparsely, mostly in members of the genus Burkholderia. Members often occur as tandem homologous genes, such as BMA_0021 and BMA_0022 in Burkholderia mallei ATCC 23344, or else have a duplication. The genes regularly are encoded near a cyclodehydrogenase/docking protein fusion protein of TOMM (thiazole/oxazole-modified microcins) biosynthetic clusters, suggesting a role in bacteriocin biosynthesis. The role of the putative natural product is unknown, but function as a two-chain bacteriocin is suggested.
Genome PropertyGenProp0901: post-ribosomal natural product synthesis system, Burkholderia TOMM-type (HMM)