HMM Summary Page: TIGR03802

Functionaspartate-alanine antiporter
Gene SymbolaspT
Trusted Cutoff546.95
Domain Trusted Cutoff546.95
Noise Cutoff418.90
Domain Noise Cutoff418.90
Isology Typeequivalog
HMM Length562
Gene Ontology TermGO:0015300: solute:solute antiporter activity molecular_function
AuthorHaft DH
Entry DateAug 12 2009 3:37PM
Last ModifiedFeb 14 2011 3:27PM
CommentAll members of the seed alignment for this model are asparate-alanine anti-transporters (AspT) encoded next to the gene for aspartate 4-decarboxylase (AspD), which converts asparate to alanine, releasing CO2. The exchange of Asp for Ala is electrogenic, so the AspD/AspT system confers a proton-motive force. This transporter contains two copies of the AspT/YidE/YbjL antiporter duplication domain (TIGR01625).
ReferencesRN [1] RM PMID:12003930 RT Plasmid-encoded asp operon confers a proton motive metabolic cycle catalyzed by an aspartate-alanine exchange reaction. RA Abe K, Ohnishi F, Yagi K, Nakajima T, Higuchi T, Sano M, Machida M, Sarker RI, Maloney PC RL J Bacteriol. 2002 Jun;184(11):2906-13.
Genome PropertyGenProp0867: decarboxylation/antiport proton-motive cycle: aspartate-alanine (HMM)