HMM Summary Page: TIGR03854

Functionprobable F420-dependent oxidoreductase, MSMEG_3544 family
Trusted Cutoff295.60
Domain Trusted Cutoff295.60
Noise Cutoff156.60
Domain Noise Cutoff156.60
Isology Typehypoth_equivalog
HMM Length290
AuthorHaft DH
Entry DateOct 9 2009 11:50AM
Last ModifiedFeb 14 2011 3:27PM
CommentCoenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (PF00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a small family, closely related to other such families in the putative F420-binding region, exemplified by MSMEG_3544 in Mycobacterium smegmatis.
ReferencesRN [1] RM PMID:20675471 RT Unexpected abundance of coenzyme F(420)-dependent enzymes in Mycobacterium tuberculosis and other actinobacteria. RA Selengut JD, Haft DH RL J Bacteriol. 2010 Nov;192(21):5788-98
Genome PropertyGenProp0002: coenzyme F420 utilization (HMM)