HMM Summary Page: TIGR03855

Functionaspartate dehydrogenase
Gene SymbolnadX
Trusted Cutoff206.55
Domain Trusted Cutoff206.55
Noise Cutoff190.70
Domain Noise Cutoff190.70
Isology Typeequivalog
EC Number1.4.1.21
HMM Length229
AuthorHaft DH
Entry DateOct 9 2009 1:01PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are L-aspartate dehydrogenase, as shown for the NADP-dependent enzyme TM_1643 of Thermotoga maritima. Members lack homology to NadB, the aspartate oxidase (EC of most mesophilic bacteria (described by TIGR00551), which this enzyme replaces in the generation of oxaloacetate from aspartate for the NAD biosynthetic pathway. All members of the seed alignment are found adjacent to other genes of NAD biosynthesis, although other uses of L-aspartate dehydrogenase may occur.
Genome PropertyGenProp0057: NAD(P) biosynthesis from L-aspartate and DHAP (HMM)