Accession | TIGR03882 |
Name | cyclo_dehyd_2 |
Function | bacteriocin biosynthesis cyclodehydratase domain |
Trusted Cutoff | 36.90 |
Domain Trusted Cutoff | 36.90 |
Noise Cutoff | 31.90 |
Domain Noise Cutoff | 31.90 |
Isology Type | equivalog_domain |
EC Number | 6.3.-.- |
HMM Length | 164 |
Author | Haft DH |
Entry Date | Nov 4 2009 8:07PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This model describes a ThiF-like domain of a fusion protein found in clusters associated with the production of TOMMs (thiazole/oxazole-modified microcins), small bacteriocins with characteristic heterocycle modifications. This domain is presumed to act as a cyclodehydratase, as do members of the SagC family modeled by TIGR03603. |
References | RN [1]
RM PMID:18375757
RT Discovery of a widely distributed toxin biosynthetic gene cluster.
RA Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE
RL Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5879-84. |
Genome Property | GenProp0807: bacteriocin system, heterocycle biosynthesis group (HMM) |
| GenProp0901: post-ribosomal natural product synthesis system, Burkholderia TOMM-type (HMM-CLUST) |