HMM Summary Page: TIGR03882

Functionbacteriocin biosynthesis cyclodehydratase domain
Trusted Cutoff36.90
Domain Trusted Cutoff36.90
Noise Cutoff31.90
Domain Noise Cutoff31.90
Isology Typeequivalog_domain
EC Number6.3.-.-
HMM Length164
AuthorHaft DH
Entry DateNov 4 2009 8:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes a ThiF-like domain of a fusion protein found in clusters associated with the production of TOMMs (thiazole/oxazole-modified microcins), small bacteriocins with characteristic heterocycle modifications. This domain is presumed to act as a cyclodehydratase, as do members of the SagC family modeled by TIGR03603.
ReferencesRN [1] RM PMID:18375757 RT Discovery of a widely distributed toxin biosynthetic gene cluster. RA Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE RL Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5879-84.
Genome PropertyGenProp0807: bacteriocin system, heterocycle biosynthesis group (HMM)
GenProp0901: post-ribosomal natural product synthesis system, Burkholderia TOMM-type (HMM-CLUST)