| Accession | TIGR03910 |
| Name | pyrrolys_PylB |
| Function | pyrrolysine biosynthesis radical SAM protein |
| Gene Symbol | pylB |
| Trusted Cutoff | 348.20 |
| Domain Trusted Cutoff | 348.20 |
| Noise Cutoff | 347.90 |
| Domain Noise Cutoff | 347.90 |
| Isology Type | equivalog |
| HMM Length | 347 |
| Author | Haft DH |
| Entry Date | Jan 5 2010 3:20PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes a radical SAM protein, PylB, that is part of the three-gene cassette sufficient for the biosynthesis of pyrrolysine (the twenty-second amino acid) when expressed heterologously in E. coli. The pyrrolysine next is ligated to its own tRNA and incorporated at special UAG codons. |
| References | RN [1]
RM PMID:17204561
RT A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine.
RA Longstaff DG, Larue RC, Faust JE, Mahapatra A, Zhang L, Green-Church KB, Krzycki JA
RL Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1021-6. |
| Genome Property | GenProp0312: pyrrolysine (HMM) |
