| Accession | TIGR03939 |
| Name | PGA_TPR_OMP |
| Function | poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA |
| Gene Symbol | pgaA |
| Trusted Cutoff | 366.65 |
| Domain Trusted Cutoff | 366.65 |
| Noise Cutoff | 288.00 |
| Domain Noise Cutoff | 288.00 |
| Isology Type | equivalog |
| HMM Length | 800 |
| Author | Haft DH |
| Entry Date | Feb 12 2010 3:11PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are the poly-beta-1,6 N-acetyl-D-glucosamine (PGA) export porin PgaA of Gram-negative bacteria. There is no counterpart in the poly-beta-1,6 N-acetyl-D-glucosamine biosynthesis systems of Gram-positive bacteria such as Staphylococcus epidermidis. The PGA polysaccharide adhesin is a critical determinant of biofilm formation. The conserved C-terminal domain of this outer membrane protein is preceded by a variable number of TPR repeats. |
| References | RN [1]
RM PMID:15090514
RT The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation.
RA Wang X, Preston JF 3rd, Romeo T
RL J Bacteriol. 2004 May;186(9):2724-34. |
| Genome Property | GenProp0907: poly-beta-1,6 N-acetyl-D-glucosamine system, PgaABCD type (HMM) |
