HMM Summary Page: TIGR03946

AccessionTIGR03946
Nameviomycin_VioC
Functionarginine beta-hydroxylase, Fe(II)/alpha-ketoglutarate-dependent
Gene SymbolvioC
Trusted Cutoff418.60
Domain Trusted Cutoff418.60
Noise Cutoff216.15
Domain Noise Cutoff216.15
Isology Typeequivalog
EC Number1.14.-.-
HMM Length333
AuthorHaft DH
Entry DateFeb 25 2010 1:52PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this protein family are L-arginine beta-hydroxylase, members of a broader family of enzymes dependent on Fe(II), alpha-ketoglutarate, and molecular oxygen. Enzymes in the broader family but excluded by this model include clavaminate synthase, taurine dioxygenase, and prolyl-4-hydroxylase.
ReferencesRN [1] RM PMID:19490124 RT Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis. RA Helmetag V, Samel SA, Thomas MG, Marahiel MA, Essen LO RL FEBS J. 2009 Jul;276(13):3669-82. Epub 2009 May 26. RN [2] RM PMID:17967013 RT CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases. RA Neidig ML, Brown CD, Light KM, Fujimori DG, Nolan EM, Price JC, Barr EW, Bollinger JM Jr, Krebs C, Walsh CT, Solomon EI RL J Am Chem Soc. 2007 Nov 21;129(46):14224-31. Epub 2007 Oct 30.
Genome PropertyGenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)
GenProp0909: capreomycidine biosynthesis (HMM)