HMM Summary Page: TIGR03962

Functionmycofactocin radical SAM maturase
Gene SymbolmftC
Trusted Cutoff265.00
Domain Trusted Cutoff265.00
Noise Cutoff225.00
Domain Noise Cutoff225.00
Isology Typeequivalog
HMM Length339
AuthorHaft DH
Entry DateMar 19 2010 4:41PM
Last ModifiedJun 20 2012 11:45AM
CommentMembers of this family are uncharacterized radical SAM proteins from the Mycobacterium tuberculosis and many other Actinobacteria, as well as some deltaproteobacteria (e.g. Geobacter uraniireducens), firmicutes (Pelotomaculum thermopropionicum and Desulfotomaculum acetoxidans), and Chloroflexi (Thermomicrobium roseum DSM 5159 and Sphaerobacter thermophilus DSM 20745). They resemble several characterized radical SAM enzymes of peptide modification (PqqE, AlbA), and are always found next to the proposed target, TIGR03969, the putative mycofactocin precursor.
ReferencesRN [1] RM PMID:21223593 RT Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners. RA Haft DH RL BMC Genomics. 2011 Jan 11;12(1):21.
Genome PropertyGenProp0917: mycofactocin system (HMM)