| Accession | TIGR03974 |
| Name | rSAM_six_Cys |
| Function | SCIFF radical SAM maturase |
| Gene Symbol | scfB |
| Trusted Cutoff | 425.00 |
| Domain Trusted Cutoff | 425.00 |
| Noise Cutoff | 380.00 |
| Domain Noise Cutoff | 380.00 |
| Isology Type | hypoth_equivalog |
| HMM Length | 451 |
| Author | Haft DH |
| Entry Date | Mar 25 2010 12:58PM |
| Last Modified | Jul 5 2011 12:49PM |
| Comment | Members of this protein family are predicted radical SAM enzymes universally associated with Six Cysteines in Forty-Five protein, or SCIFF (family TIGR03973), a predicted ribosomal natural product precursor that is nearly universal in the class Clostridia. Similarity of this family to radical SAM maturases (PqqE and subtilosin A maturase) found in the vicinity of other peptide precursors suggests this protein is the SCIFF radical SAM maturase. |
| References | RN [1]
RM PMID:21478363
RT Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification.
RA Haft DH, Basu MK
RL J Bacteriol. 2011 Jun;193(11):2745-55. |
| Genome Property | GenProp0919: SCIFF/radical SAM Clostridial gene pair (HMM) |
