| Accession | TIGR03979 |
| Name | His_Ser_Rich |
| Function | His-Xaa-Ser repeat protein HxsA |
| Gene Symbol | hxsA |
| Trusted Cutoff | 121.65 |
| Domain Trusted Cutoff | 121.65 |
| Noise Cutoff | 63.80 |
| Domain Noise Cutoff | 63.80 |
| Isology Type | hypoth_equivalog |
| HMM Length | 190 |
| Author | Haft DH |
| Entry Date | Apr 4 2010 2:07PM |
| Last Modified | Jun 9 2011 9:49AM |
| Comment | Members of this protein share two defining regions. One is a histidine/serine-rich cluster, typically H-R-S-H-S-S-H-R-S-H-S-S-H. Members are found always in the context of a pair of radical SAM proteins, HxsB and HxsC, and a fourth protein HxsD. The system is predicted to perform peptide modifications, likely in the His-Xaa-Ser region, to produce some uncharacterized natural product. |
| References | DR PFAM; PF01471; Putative peptidoglycan binding domain
RN [1]
RM PMID:21478363
RT Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational mo
dification.
RA Haft DH, Basu MK
RL J Bacteriol. 2011 Jun;193(11):2745-55. |
| Genome Property | GenProp0921: radical SAM pair and His-Xaa-Ser repeats peptide (HMM) |
