HMM Summary Page: TIGR03989

AccessionTIGR03989
NameRxyl_3153
FunctionNDMA-dependent alcohol dehydrogenase, Rxyl_3153 family
Trusted Cutoff440.00
Domain Trusted Cutoff440.00
Noise Cutoff360.00
Domain Noise Cutoff360.00
Isology Typesubfamily
EC Number1.1.99.36
HMM Length370
AuthorHaft DH
Entry DateApr 19 2010 4:18PM
Last ModifiedFeb 15 2012 9:21AM
CommentThis HMM describes a clade within the family PF00107 of zinc-binding dehydrogenases. The family PF00107 contains class III alcohol dehydrogenases, including enzymes designated S-(hydroxymethyl)glutathione dehydrogenase and NAD/mycothiol-dependent formaldehyde dehydrogenase. Members of the current family occur only in species that contain the very small protein mycofactocin (TIGR03969), a possible cofactor precursor, and radical SAM protein TIGR03962. We name this family for Rxyl_3153, where the lone member of the family co-clusters with these markers in Rubrobacter xylanophilus.
ReferencesRN [1] RM PMID:21223593 RT Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners. RA Haft DH RL BMC Genomics. 2011 Jan 11;12(1):21.
Genome PropertyGenProp0917: mycofactocin system (HMM)