HMM Summary Page: TIGR04012

Functionpoly-gamma-glutamate synthase PgsB
Gene SymbolpgsB
Trusted Cutoff222.70
Domain Trusted Cutoff222.70
Noise Cutoff116.35
Domain Noise Cutoff116.35
Isology Typeequivalog
EC Number6.3.2.-
HMM Length380
AuthorHaft DH
Entry DateJun 3 2010 4:13PM
Last ModifiedFeb 14 2011 3:27PM
CommentOf four genes commonly found to be involved in biosynthesis and export of poly-gamma-glutamate, pgsB(capB) and pgsC(capC) are found to be involved in the synthesis per se. Members of this family are designated PgsB, a nomeclature that covers both cases in which the poly-gamma-glutamate is secreted and those in which it is retained to form capsular material.PgsB has been shown to have poly-gamma-glutamate activity by itself but is bound tightly by PgsC (TIGR04011).
ReferencesRN [1] RM PMID:16689787 RT Poly-gamma-glutamate in bacteria. RA Candela T, Fouet A RL Mol Microbiol. 2006 Jun;60(5):1091-8.
Genome PropertyGenProp0822: poly(gamma-glutamic acid) biosynthesis (HMM)