HMM Summary Page: TIGR04055
| Accession | TIGR04055 |
| Name | rSAM_NirJ2 |
| Function | putative heme d1 biosynthesis radical SAM protein NirJ2 |
| Gene Symbol | nirJ2 |
| Trusted Cutoff | 500.00 |
| Domain Trusted Cutoff | 500.00 |
| Noise Cutoff | 425.00 |
| Domain Noise Cutoff | 425.00 |
| Isology Type | equivalog |
| EC Number | 1.3.99.- |
| HMM Length | 326 |
| Author | Haft DH |
| Entry Date | Jul 28 2010 10:37AM |
| Last Modified | Jun 27 2014 1:54PM |
| Comment | Members of this radical SAM protein subfamily, designated NirJ2, occur in genomic contexts with a paralog NirJ1 and with other nitrite reductase operon genes associated with heme d1 biosynthesis, as in Heliobacillus mobilis and Heliophilum fasciatum. NirJ2 is presumed by bioinformatics analysis (Xiong, et al.) to be a heme d1 biosynthesis protein by context. This model has been redone (2014) to remove the branch (TIGR04545) that included DVU_0855, from a similar pathway for heme b biosynthesis. |
| References | RN [1] RM PMID:17906152 RT Insight into the haem d1 biosynthesis pathway in heliobacteria through bioinformatics analysis. RA Xiong J, Bauer CE, Pancholy A RL Microbiology. 2007 Oct;153(Pt 10):3548-62. |