HMM Summary Page: TIGR04064

Functionnif11-like peptide radical SAM maturase
Gene SymbolnlpM
Trusted Cutoff518.70
Domain Trusted Cutoff518.70
Noise Cutoff313.30
Domain Noise Cutoff313.30
Isology Typeequivalog
HMM Length459
AuthorHaft DH
Entry DateSep 15 2010 12:34PM
Last ModifiedMay 24 2011 3:49PM
CommentMembers of this family are radical SAM enzymes that occur co-clustered with nif11-related ribosomal natural product (RNP) precursors described by TIGRFAMs model TIGR03798. Homology within the bacteriocin family reflects largely constraints on the leader peptide, tied to processes such as cleavage and export, and members associate with various families of maturation enzyme. The gene symbol assigned is nlpM, for Nif11-class Leader Peptide family Radical SAM Maturase.
ReferencesRN [1] RM PMID:20500830 RT Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family. RA Haft DH, Basu MK, Mitchell DA RL BMC Biol. 2010 May 25;8:70.
Genome PropertyGenProp0861: bacteriocin system, NHLP (nif11/nitrile hydratase leader peptide) transport group (HMM)