HMM Summary Page: TIGR04066

Functionpeptide maturation system protein, TIGR04066 family
Trusted Cutoff200.00
Domain Trusted Cutoff200.00
Noise Cutoff125.00
Domain Noise Cutoff125.00
Isology Typehypoth_equivalog
HMM Length361
AuthorHaft DH
Entry DateOct 5 2010 1:51PM
Last ModifiedJun 9 2011 9:55AM
CommentMembers of this protein family occur in various Clostridial genomes, always in the context of a short peptide and a radical SAM protein predicted to modify the short peptide. PSI-BLAST analysis suggests a sequence relationship to archaeal proteins designated as subunits of an H+-transporting two-sector ATPase. The modified peptide is likely to be a bacteriocin, and this protein is a candidate to act in either maturation or immunity.
ReferencesRN [1] RM PMID:21478363 RT Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification. RA Haft DH, Basu MK RL J Bacteriol. 2011 Jun;193(11):2745-55.
Genome PropertyGenProp0945: radical SAM maturase bacteriocin system, CLI_3235 type (HMM)