| Accession | TIGR04077 |
| Name | expor_sig_YdyF |
| Function | exported signaling peptide, YydF/SAG_2028 family |
| Trusted Cutoff | 35.00 |
| Domain Trusted Cutoff | 35.00 |
| Noise Cutoff | 25.00 |
| Domain Noise Cutoff | 25.00 |
| Isology Type | subfamily |
| HMM Length | 49 |
| Author | Haft DH |
| Entry Date | Oct 28 2010 12:27PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This family describes a rare family of small proteins, about 50 residues in length, that includes YydF from Bacillus subtilis and SAG_2028 from Streptococcus agalactiae 2603V/R. Mutational analysis and genomic context show that members of this family likely are modified by a (variably present) radical SAM enzyme, are exported by an ABC transporter, and serve as signaling peptide. The member from Bacillus subtilis induces the LiaRS two-component system. |
| References | RN [1]
RM PMID:17921301
RT The yydFGHIJ operon of Bacillus subtilis encodes a peptide that induces the LiaRS two-component system.
RA Butcher BG, Lin YP, Helmann JD
RL J Bacteriol. 2007 Dec;189(23):8616-25. Epub 2007 Oct 5. |
| Genome Property | GenProp0955: modified peptide/radical SAM maturase system, YydFG family (HMM) |
