HMM Summary Page: TIGR04080

FunctionKxxxW cyclic peptide radical SAM maturase
Gene SymbolkwcM
Trusted Cutoff500.00
Domain Trusted Cutoff500.00
Noise Cutoff100.00
Domain Noise Cutoff100.00
Isology Typeequivalog
HMM Length440
AuthorHaft DH
Entry DateOct 29 2010 9:58AM
Last ModifiedMay 12 2011 12:18PM
CommentMembers of this family are radical SAM enzymes that appear to perform a cyclization on an adjacent cognate peptide from family TIGR04079. Genomes with the complete system include Streptococcus thermophilus LMD-9 and Lactococcus lactis subsp. cremoris MG1363, among others. The gene symbol assigned is kwcM, for KxxxW Cyclic peptide Maturase.
ReferencesRN [1] RM PMID:17921293 RT Control of the transcription of a short gene encoding a cyclic peptide in Streptococcus thermophilus: a new quorum-sensing system? RA Ibrahim M, Guillot A, Wessner F, Algaron F, Besset C, Courtin P, Gardan R, Monnet V RL J Bacteriol. 2007 Dec;189(24):8844-54. Epub 2007 Oct 5.
Genome PropertyGenProp0954: radical SAM-cylized peptide, Pep1357C family (HMM)