| Accession | TIGR04081 |
| Name | selen_ocin |
| Function | radical SAM modification target peptide, selenobiotic family |
| Trusted Cutoff | 32.00 |
| Domain Trusted Cutoff | 32.00 |
| Noise Cutoff | 28.00 |
| Domain Noise Cutoff | 28.00 |
| Isology Type | subfamily |
| HMM Length | 37 |
| Author | Haft DH |
| Entry Date | Nov 1 2010 1:45PM |
| Last Modified | Jun 9 2011 10:19AM |
| Comment | Members of this protein family are small peptides found in the vicinity of a peptide modification-type radical SAM protein family. Multiple members of this protein family occur in species with a selenocysteine incorporation systems and have a TGA stop codon at position that aligns with cysteine residues from other homologs. This finding strongly suggests that GSU_1558 and similar members of the family are selenopeptides. The selenocysteine insertion sequence (SECIS) finder bSECISearch finds two homologous SECIS elements for two TGA codons in the extension of GSU_1558. Meanwhile, the pairing with the radical SAM enzyme suggests additional modification. |
| References | RN [1]
RM PMID:21478363
RT Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification.
RA Haft DH, Basu MK
RL J Bacteriol. 2011 Jun;193(11):2745-55. |
| Genome Property | GenProp0956: radical SAM maturase/selenobacteriocin system (HMM) |
