Accession | TIGR04107 |
Name | rSAM_HutW |
Function | putative heme utilization radical SAM enzyme HutW |
Gene Symbol | hutW |
Trusted Cutoff | 400.00 |
Domain Trusted Cutoff | 400.00 |
Noise Cutoff | 275.00 |
Domain Noise Cutoff | 275.00 |
Isology Type | equivalog |
HMM Length | 419 |
Author | Haft DH |
Entry Date | Jan 26 2011 11:00AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | HutW is a radical SAM enzyme closely related to HemN, the heme biosynthetic oxygen-independent coproporphyrinogen oxidase. It belongs to operons associated with heme uptake and utilization in Vibrio cholerae and related species, but neither it not HutX has been shown to be needed, as is HutZ, for heme utilization. HutW failed to complement a Salmonella enterica hemN mutant (PMID:15205415), suggesting a related but distinct activity. Some members of this family are fused to hutX. |
References | RN [1]
RM PMID:15205415
RT HutZ is required for efficient heme utilization in Vibrio cholerae.
RA Wyckoff EE, Schmitt M, Wilks A, Payne SM
RL J Bacteriol. 2004 Jul;186(13):4142-51. |
Genome Property | GenProp0961: heme metabolism pair HutWX (HMM) |