| Accession | TIGR04114 |
| Name | tSAM_targ_Cxxx |
| Function | modification target Cys-rich repeat |
| Trusted Cutoff | 20.00 |
| Domain Trusted Cutoff | 13.50 |
| Noise Cutoff | 16.00 |
| Domain Noise Cutoff | 13.30 |
| Isology Type | repeat |
| HMM Length | 18 |
| Author | Haft DH |
| Entry Date | Feb 5 2011 3:22PM |
| Last Modified | Aug 2 2011 2:33PM |
| Comment | This HMM describes a cysteine-rich repeat found in a number of bacterial putative radical-SAM modified natural product precursors. A substantial fraction of members of this family have been missed during gene-finding. A true hit to the model must exceed both TC on the whole and trusted cutoff 2 for at least one domain, to avoid false-positives from African swine fever virus proteins. |
| References | RN [1]
RM PMID:21478363
RT Biological systems discovery in silico: radical S-adenosylmethionine protein families and their target peptides for posttranslational modification.
RA Haft DH, Basu MK
RL J Bacteriol. 2011 Jun;193(11):2745-55. |
| Genome Property | GenProp0967: radical SAM maturase system, CXXX repeats type (HMM) |