| Accession | TIGR04125 |
| Name | exosort_PGF_TRM |
| Function | archaeosortase A |
| Gene Symbol | artA |
| Trusted Cutoff | 75.00 |
| Domain Trusted Cutoff | 75.00 |
| Noise Cutoff | 60.00 |
| Domain Noise Cutoff | 60.00 |
| Isology Type | equivalog |
| EC Number | 3.4.22.- |
| HMM Length | 271 |
| Author | Haft DH |
| Entry Date | Feb 11 2011 12:05PM |
| Last Modified | Feb 10 2012 10:53AM |
| Comment | This family is an archaeal variant of the (normally bacterial) putative protein-sorting integral membrane protein exosortase, hence archaeosortase. In species a member of this family, its PGF-CTERM cognate sequence (TIGR04126) occurs at the C-termini of from two to over fifty proteins per genome. Those target proteins may not share homology to each other in regions N-terminal to the PGF-CTERM region. |
| References | RN [1]
RM PMID:22037399
RT Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification.
RA Haft DH, Payne SH, Selengut JD
RL J Bacteriol. 2012 Jan;194(1):36-48. |
| Genome Property | GenProp0978: protein sorting system, PGF-CTERM/archaeosortase A (HMM) |
