HMM Summary Page: TIGR04125

Functionarchaeosortase A
Gene SymbolartA
Trusted Cutoff75.00
Domain Trusted Cutoff75.00
Noise Cutoff60.00
Domain Noise Cutoff60.00
Isology Typeequivalog
EC Number3.4.22.-
HMM Length271
AuthorHaft DH
Entry DateFeb 11 2011 12:05PM
Last ModifiedFeb 10 2012 10:53AM
CommentThis family is an archaeal variant of the (normally bacterial) putative protein-sorting integral membrane protein exosortase, hence archaeosortase. In species a member of this family, its PGF-CTERM cognate sequence (TIGR04126) occurs at the C-termini of from two to over fifty proteins per genome. Those target proteins may not share homology to each other in regions N-terminal to the PGF-CTERM region.
ReferencesRN [1] RM PMID:22037399 RT Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification. RA Haft DH, Payne SH, Selengut JD RL J Bacteriol. 2012 Jan;194(1):36-48.
Genome PropertyGenProp0978: protein sorting system, PGF-CTERM/archaeosortase A (HMM)