HMM Summary Page: TIGR04301

Functionornithine decarboxylase SpeF
Gene SymbolspeF
Trusted Cutoff1310.00
Domain Trusted Cutoff1310.00
Noise Cutoff1305.00
Domain Noise Cutoff1305.00
Isology Typeexception
EC Number4.1.1.17
HMM Length719
AuthorHaft DH
Entry DateMar 23 2012 10:11AM
Last ModifiedMar 23 2012 10:19AM
CommentMembers of this family are known or trusted examples of ornithine decarboxylase, all encoded in the immediate vicinity of an ornithine-putrescine antiporter. Decarboxylation of ornithine to putrescine, followed by exchange of a putrescine for a new ornithine, is a proton-motive cycle that can be induced by low pH and protect a bacterium against transient exposure to acidic conditions.
ReferencesRN [1] RM PMID:22247134 RT Evidence of two functionally distinct ornithine decarboxylation systems in lactic Acid bacteria. RA Romano A, Trip H, Lonvaud-Funel A, Lolkema JS, Lucas PM RL Appl Environ Microbiol. 2012 Mar;78(6):1953-61.
Genome PropertyGenProp0643: putrescine biosynthesis from arginine via ornithine (HMM)
GenProp0871: decarboxylation/antiport proton-motive cycle: ornithine-putrescine (HMM)