HMM Summary Page: TIGR04335

FunctionAmmeMemoRadiSam system protein A
Gene SymbolamrA
Trusted Cutoff99.00
Domain Trusted Cutoff99.00
Noise Cutoff96.00
Domain Noise Cutoff96.00
Isology Typehypoth_equivalog
HMM Length175
AuthorHaft DH
Entry DateJun 5 2012 12:10PM
Last ModifiedAug 12 2012 6:56PM
CommentMembers of this protein family belong to the same domain family as AMMECR1, a mammalian protein named for AMME - Alport syndrome, Mental Retardation, Midface hypoplasia, and Elliptocytosis. Members of the present family occur as part of a three gene system with a homolog of the mammalian protein Memo (Mediator of ErbB2-driven cell MOtility), and an uncharacterized radical SAM enzyme.
ReferencesRN [1] RM PMID:17715145 RT The RAGNYA fold: a novel fold with multiple topological variants found in functionally diverse nucleic acid, nucleotide and peptide-binding proteins. RA Balaji S, Aravind L RL Nucleic Acids Res. 2007;35(17):5658-71.
Genome PropertyGenProp1063: Memo/AMMECR1/rSAM family trio system (HMM)