HMM Summary Page: TIGR04367

Functionhopanoid C-3 methylase HpnR
Gene SymbolhpnR
Trusted Cutoff650.00
Domain Trusted Cutoff650.00
Noise Cutoff350.00
Domain Noise Cutoff350.00
Isology Typeequivalog
HMM Length490
AuthorHaft DH
Entry DateAug 9 2012 1:56PM
Last ModifiedAug 12 2012 6:56PM
CommentMembers of this are family are a B12-binding domain/radical SAM domain protein required for 3-methylhopanoid production. Activity was confirmed by mutant phenotype by disrupting this gene in Methylococcus capsulatus strain Bath. This protein family should only occur in genomes that encode a squalene-hopene cyclase (see TIGR01507).
ReferencesRN [1] RM PMID:22826256 RT Discovery, taxonomic distribution, and phenotypic characterization of a gene required for 3-methylhopanoid production. RA Welander PV, Summons RE RL Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):12905-10. Epub 2012 Jul 23.
Genome PropertyGenProp0761: hopanoid lipid biosynthesis (HMM)