HMM Summary Page: TIGR04414

Functionautotransporter strand-loop-strand O-heptosyltransferase
Trusted Cutoff200.00
Domain Trusted Cutoff200.00
Noise Cutoff65.00
Domain Noise Cutoff65.00
Isology Typeequivalog
EC Number2.4.1.-
HMM Length374
AuthorHaft DH
Entry DateFeb 11 2013 8:28AM
Last ModifiedFeb 11 2013 8:28AM
CommentBoth Aah (autotransporter adhesin heptosyltransferase) and TibC (tib is enterotoxigenic invasion locus B) are protein O-heptosyltransferases that act on multiple sites from repeat regions of proteins exported by autotransporters. Aah glycosylates AIDA, or autotransporter adhesin involved in diffuse adherence, TibC acts on TibA, but TibC can replace Aah.
ReferencesRN [1] RM PMID:11953358 RT Functional substitution of the TibC protein of enterotoxigenic Escherichia coli strains for the autotransporter adhesin heptosyltransferase of the AIDA system. RA Moormann C, Benz I, Schmidt MA RL Infect Immun. 2002 May;70(5):2264-70. RN [2] RM PMID:22221153 RT N for AsN - O for strOcture? A strand-loop-strand motif for prokaryotic O-glycosylation. RA Otzen D RL Mol Microbiol. 2012 Mar;83(5):879-83.
Genome PropertyGenProp1080: protein O-heptosyltransferase with autotransporter target (HMM)