HMM Summary Page: TIGR04415

Functionautotransporter passenger strand-loop-strand repeat
Trusted Cutoff30.00
Domain Trusted Cutoff20.00
Noise Cutoff20.00
Domain Noise Cutoff16.00
Isology Typerepeat
HMM Length38
AuthorHaft DH
Entry DateFeb 11 2013 3:59PM
Last ModifiedFeb 11 2013 3:59PM
CommentThis model describes two tandem copies of a strand-loop-strand repeat that occurs often in type V secretion system (T5SS). These repeats usually occur in the passenger domain of the classical monomeric autotransporter. Proteins with this repeat often are encoded next to a member of family TIGR04414, the Aah/TibC family O-heptosyltransferase, and may be glycosylated in regions with this repeat.
ReferencesRN [1] RM PMID:11953358 RT Functional substitution of the TibC protein of enterotoxigenic Escherichia coli strains for the autotransporter adhesin heptosyltransferase of the AIDA system. RA Moormann C, Benz I, Schmidt MA RL Infect Immun. 2002 May;70(5):2264-70. RN [2] RM PMID:22221153 RT N for AsN - O for strOcture? A strand-loop-strand motif for prokaryotic O-glycosylation. RA Otzen D RL Mol Microbiol. 2012 Mar;83(5):879-83.
Genome PropertyGenProp1080: protein O-heptosyltransferase with autotransporter target (HMM-CLUST)