HMM Summary Page: TIGR04472

Functionmobile rSAM pair MarR family regulator
Trusted Cutoff240.00
Domain Trusted Cutoff240.00
Noise Cutoff200.00
Domain Noise Cutoff200.00
Isology Typehypoth_equivalog
HMM Length141
AuthorHaft DH
Entry DateAug 25 2013 8:10PM
Last ModifiedAug 25 2013 8:10PM
CommentA number of human microbiome species from both the Firmicutes and the spirochete genus Treponema share a gene cassette encoding a pair of radical SAM enzymes and, in most cases, this MarR family transcriptional regulator as well. Sequence identity can exceed 96 percent, suggesting recent lateral transfer. These observations suggest the cassette confers resistance to a toxic compound such as an antibiotic.
Genome PropertyGenProp1086: Firmicutes/Treponema mobile radical SAM system (HMM)