HMM Summary Page: TIGR04472
| Accession | TIGR04472 |
| Name | reg_rSAM_mob |
| Function | mobile rSAM pair MarR family regulator |
| Trusted Cutoff | 240.00 |
| Domain Trusted Cutoff | 240.00 |
| Noise Cutoff | 200.00 |
| Domain Noise Cutoff | 200.00 |
| Isology Type | hypoth_equivalog |
| HMM Length | 141 |
| Author | Haft DH |
| Entry Date | Aug 25 2013 8:10PM |
| Last Modified | Aug 25 2013 8:10PM |
| Comment | A number of human microbiome species from both the Firmicutes and the spirochete genus Treponema share a gene cassette encoding a pair of radical SAM enzymes and, in most cases, this MarR family transcriptional regulator as well. Sequence identity can exceed 96 percent, suggesting recent lateral transfer. These observations suggest the cassette confers resistance to a toxic compound such as an antibiotic. |
| Genome Property | GenProp1086: Firmicutes/Treponema mobile radical SAM system (HMM) |