HMM Summary Page: TIGR04508
Accession | TIGR04508 |
Name | queE_Cx14CxxC |
Function | 7-carboxy-7-deazaguanine synthase |
Gene Symbol | queE |
Trusted Cutoff | 240.00 |
Domain Trusted Cutoff | 240.00 |
Noise Cutoff | 200.00 |
Domain Noise Cutoff | 200.00 |
Isology Type | equivalog |
EC Number | 4.3.99.3 |
HMM Length | 208 |
Author | Haft DH |
Entry Date | Jan 22 2014 12:08PM |
Last Modified | Jan 22 2014 12:08PM |
Comment | In the pathway of 7-cyano-7-deazaquanine (preQ0) biosynthesis, the radical SAM enzyme QueE is quite variable. This HMM describes a variant form in which the three-Cys motif that binds the signature 4Fe-4S cluster takes the form Cx14CxxC, as in Burkholderia multivorans ATCC 17616. The crystal structure is known. |