|Function||encapsulation C-terminal sorting signal|
|Domain Trusted Cutoff||11.00|
|Domain Noise Cutoff||10.80|
|Entry Date||May 15 2014 11:28AM|
|Last Modified||Sep 16 2014 4:02PM|
|Comment||This model describes a diverse region of extremely small size (11 residues), so unavoidably there are both false-positives and false-negatives. All true hits should occur in proteins encoded next to an encapsulating protein (see PF04454), and should occur near the extreme C-terminus. Families previously known to have this domain on some members to mediate encapsulation include dye-decolorizing peroxidases and a ferritin-like protein, but (as this model helps show) there are others, including some hemerythrin family proteins and novel family TIGR04536.|
RT Assembly in vitro of Rhodococcus jostii RHA1 encapsulin and peroxidase DypB to form a nanocompartment.
RA Rahmanpour R, Bugg TD
RL FEBS J. 2013 May;280(9):2097-104. doi: 10.1111/febs.12234.
RT Structural basis of enzyme encapsulation into a bacterial nanocompartment.
RA Sutter M, Boehringer D, Gutmann S, Gunther S, Prangishvili D, Loessner MJ, Stetter KO, Weber-Ban E, Ban N
RL Nat Struct Mol Biol. 2008 Sep;15(9):939-47. doi: 10.1038/nsmb.1473.|
|Genome Property||GenProp0810: encapsulin proteinaceous organelle (HMM)|
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