JCVI: About / Bios / Appolinaire Djikeng
 
 
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About

Biographies

Appolinaire Djikeng, Ph.D.
Staff Scientist III

Research Interests and Accomplishments

Dr. Djikeng graduated with BSC (Honors) and MSC from the University of Yaoundé I in Cameroon. He was subsequently awarded the WHO scholarship for training in tropical diseases to pursue PhD studies jointly with the International Livestock Research Institute in Nairobi, Kenya and Brunel University in London. He then joined the Yale University School of Medicine for postdoctoral training where he made significant contributions for the discovery of the first intron in kinetoplastids, the elucidation of the RNA interference (RNAi) pathway, and developed methodologies and reagents for the use of RNAi as a tool for the regulation of gene expresion in African trypanosomes. Dr. Djikeng also served for one year as a junior faculty at the Yale School of Medicine (section of infectious diseases) before joining the JCVI.

At JCVI, Dr. Djikeng is Staff Scientist in the infectious disease group. His major interests are in the areas of research and development of new methodologies for high throughput viral genome sequencing, analysis and their application to understanding the evolution of emerging and re-emerging viruses. His long term goals are to develop new approaches to predict and control emerging and re-emerging viral infectious diseases, as well as to facilitate the transfer of technologies and knowledge in genomics and related disciplines to developing countries.

Select Publications

Djikeng, A., Halpin, R. A., et al.
Viral genome sequencing by random priming methods
BMC Genomics. 2008 Jan 07; 9(1): 5.

Berriman, M., Ghedin, E., et al.
The genome of the African trypanosome Trypanosoma brucei
Science. 2005 Jul 15; 309(5733): 416-22.

El-Sayed, N. M., Myler, P. J., et al.
Comparative genomics of trypanosomatid parasitic protozoa
Science. 2005 Jul 15; 309(5733): 404-9.

Djikeng, A., Shen, S., et al.
Analysis of gene function in Trypanosoma brucei using RNA interference
Methods Mol Biol. 2004 Jan 01; 270: 287-98.

Djikeng, A., Shi, H., et al.
An siRNA ribonucleoprotein is found associated with polyribosomes in Trypanosoma brucei
Rna. 2003 Jul 01; 9(7): 802-8.

Djikeng, A., Shi, H., et al.
RNA interference in Trypanosoma brucei: cloning of small interfering RNAs provides evidence for retroposon-derived 24-26-nucleotide RNAs
Rna. 2001 Nov 01; 7(11): 1522-30.

Mair, G., Shi, H., et al.
A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA
Rna. 2000 Feb 01; 6(2): 163-9.

 

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