JCVI: About / Bios / Derrick Fouts
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Derrick E. Fouts, Ph.D.

Research Interests and Accomplishments

Dr. Fouts is a Professor at the Rockville Campus of the JCVI. Dr. Fouts has extensive experience in viral and bacteriophage genomics, bacterial genomics, comparative genomics, and metagenomics of bacterial and viral communities. Since joining Dr. Karen Nelson's group at TIGR/JCVI in 2001, Dr. Fouts has led several microbial sequencing projects, including animal, plant and human pathogens. Many of these projects were among the first to compare multiple strains. In addition to leading projects, Dr. Fouts has developed various software tools, including applications to perform multi-genome comparisons and heuristic software (Phage_Finder) to identify prophage regions in bacterial genomes. Dr. Fouts is currently leading the JCVI effort to sequence the human virome and reference viral and bacteriophage genomes under the Human Microbiome Project.

Dr. Fouts received his B.S. degree (1992) in Biology with honors from Indiana University, Bloomington, and his M.S. (1994) and Ph.D. (1997) degrees in Microbiology from the University of Illinois Urbana/Champaign Department of Microbiology. In 1997, he began postdoctoral work in Dr. Alan Collmer's lab at Cornell University.

Select Publications

Derrick E. Fouts
Leptospiral Pathogenomics

Pathogens. 2014 Apr 10; 3: 280-308.[more]

Fouts DE, Torralba M, et al.
Bacterial Translocation and Changes In the Intestinal Microbiome In Mouse Models of Liver Disease.

Journal of hepatology. 2012 Jun 01; 56: 1283-92.[more]

Fouts, D. E., Tyler, H. L., et al.
Complete Genome Sequence of the N2-fixing Broad Host Range Endophyte Klebsiella pneumoniae 342 and Virulence Predictions Verified In Mice

PLoS Genet. 2008 Jul 25; 4(7): e1000141.[more]

Rasko, D. A., Rosovitz, M. J., et al.
Complete Sequence Analysis of Novel Plasmids from Emetic and Periodontal Bacillus cereus Isolates Reveals a Common Evolutionary History Among the B. Cereus-group Plasmids, Including Bacillus anthracis PXO1

J Bacteriol. 2007 Jan 01; 189(1): 52-64.[more]

Fouts, D. E.
Phage_Finder: Automated Identification and Classification of Prophage Regions In Complete Bacterial Genome Sequences

Nucleic Acids Res. 2006 Oct 24; 34: 5839-5851.[more]

Fouts, D. E., Rasko, D. A., et al.
Sequencing Bacillus anthracis Typing Phages Gamma and Cherry Reveals a Common Ancestry

J Bacteriol. 2006 May 01; 188(9): 3402-8.[more]

Gill, S. R., Fouts, D. E., et al.
Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-resistant Staphylococcus aureus Strain and a Biofilm-producing Methicillin-resistant Staphylococcus epidermidis Strain

J Bacteriol. 2005 Apr 01; 187(7): 2426-38.[more]

Fouts, D. E., Mongodin, E. F., et al.
Major Structural Differences and Novel Potential Virulence Mechanisms from the Genomes of Multiple Campylobacter Species

PLoS Biol. 2005 Jan 01; 3(1): e15.[more]

Venter, J. C., Remington, K., et al.
Environmental Genome Shotgun Sequencing of the Sargasso Sea

Science. 2004 Apr 02; 304(5667): 66-74.[more]

Fouts, D. E., Badel, J. L., et al.
A Pseudomonas Syringae Pv. Tomato DC3000 Hrp (Type III Secretion) Deletion Mutant Expressing the Hrp System of Bean Pathogen P. Syringae Pv. Syringae 61 Retains Normal Host Specificity for Tomato

Mol Plant Microbe Interact. 2003 Jan 01; 16(1): 43-52.[more]

Fouts, D. E., Abramovitch, R. B., et al.
Genomewide Identification of Pseudomonas Syringae Pv. Tomato DC3000 Promoters Controlled by the HrpL Alternative Sigma Factor

Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4): 2275-80.[more]

Fouts, D. E., Celander, D. W.
Translationally Repressive RNA Structures Monitored In Vivo Using Temperate DNA Bacteriophages

Gene. 1998 Mar 27; 210(1): 135-42.[more]

Fouts, D. E., True, H. L., et al.
Functional Recognition of Fragmented Operator Sites by R17/MS2 Coat Protein, a Translational Repressor

Nucleic Acids Res. 1997 Nov 15; 25(22): 4464-73.[more]

Fouts, D. E., True, H. L., et al.
Site-specific Phosphorylation of the Human Immunodeficiency Virus Type-1 Rev Protein Accelerates Formation of an Efficient RNA-binding Conformation

Biochemistry. 1997 Oct 28; 36(43): 13256-62.[more]

Fouts, D. E., Celander, D. W.
Improved Method for Selecting RNA-binding Activities In Vivo

Nucleic Acids Res. 1996 Apr 15; 24(8): 1582-4.[more]