Research Interests and Accomplishments

Dr. Granger Sutton is Senior Director of Informatics at the J. Craig Venter Institute (JCVI). Prior to joining JCVI, Dr. Sutton was a director in the Informatics Research department at Celera Genomics (from 1998 to 2004) where he developed and managed research programs in gene finding, comparative genomics, and shotgun fragment assembly including the development of the Celera Assembler for assembling the human genome. Dr. Sutton was a Computer Scientist at The Institute for Genomic Research (TIGR) (1992-1998) developing protein homology search, multiple sequence alignment, and shotgun fragment assembly algorithms. From 1982 to 1985, Dr. Sutton worked at AT&T Bell Labs as a Member of Technical Staff designing and implementing office automation software.

Dr. Sutton is the PI for Pathema, a Bioinformatics Resource Center (BRC) funded by NIAID, which provides many types of genomic and other information for several clades of pathogenic organisms to the biomedical research community. In conjunction, Dr. Sutton is investigating state of the art methods for automated, manual, and comparative structural and functional annotation.

Dr. Sutton is also the PI for an NIH funded grant to improve the Celera Assembler. Dr. Sutton continues to pursue his longstanding research into shotgun fragment assembly methods including the incorporation of the new sequencing technologies. Dr. Sutton earned his bachelor's degree in electrical engineering and doctorate in computer science from University of Maryland, College Park. He also earned a master’s degree in computer engineering from Stanford University.

Select Publications

Levy, S., G. Sutton, et al. (2007). The diploid genome sequence of an individual human. PLoS Biol 5(10): e254.

Rusch, D. B., A. L. Halpern, et al. (2007). The Sorcerer II Global Ocean Sampling expedition: northwest Atlantic through eastern tropical Pacific. PLoS Biol 5(3): e77.

Warren, R. L., G. G. Sutton, et al. (2007). Assembling millions of short DNA sequences using SSAKE. Bioinformatics 23(4): 500-1.

Yooseph, S., G. G. Sutton, et al. (2007). The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol 5(3): e16.

Goldberg, S. M., J. Johnson, et al. (2006). A Sanger/pyrosequencing hybrid approach for the generation of high-quality draft assemblies of marine microbial genomes. Proc Natl Acad Sci USA 103(30): 11240-5.

Istrail, S., G. G. Sutton, et al. (2004). Whole-genome shotgun assembly and comparison of human genome assemblies. Proc Natl Acad Sci USA 101(7): 1916-21.

Myers, E. W., G. G. Sutton, et al. (2000). A whole-genome assembly of Drosophila. Science 287(5461): 2196-204.