JCVI: About / Bios / Kelvin Li
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Kelvin Li
Senior Software Engineer

Research Interests and Accomplishments

Kelvin Li is a Senior Software Engineer in the Informatics Department at the J. Craig Venter Institute. Currently, he is involved with the research and development of high throughput algorithms and statistical analyses for both the Viral (Infectious Disease) and Microbial and Environmental Genomics groups. His work has included the analyses of 16S rDNA, ANDES (ANalyses of DEep Sequencing), VariantClassifier, computational PCR primer design, the CAMERA project, the CABOG genome assembler and the analyses of new sequencing technologies.

Prior to his work at JCVI, he was a lead software engineer at Celera Genomics, where he was involved with the design and implementation of the Human and Mouse Gene Index/Splice Variant annotation pipeline.

He received a dual B.S. degree in Computer Science and Cellular and Molecular Biology and a M.S. in Computer Science and Engineering from the University of Michigan, Ann Arbor. Later, he completed a part-time dual M.B.A. and M.S. in Finance from the Robert H. Smith School of Business at the University of Maryland, College Park. Currently, he is working towards his M.S. in Applied Statistics through the distance learning program at Texas A&M University, College Station.

Select Publications

Li K, Bihan M, et al.
Analyses of the Stability and Core Taxonomic Memberships of the Human Microbiome.

PloS One. 2013 May 01; 8: e63139.[more]

Goll J, Rusch DB, et al.
METAREP: JCVI Metagenomics Reports--an Open Source Tool for High-performance Comparative Metagenomics.

Bioinformatics (Oxford, England). 2010 Oct 15; 26: 2631-2.[more]

Li, K., Stockwell, T. B.
VariantClassifier: A Hierarchical Variant Classifier for Annotated Genomes

BMC Res Notes. 2010 Aug 01; 3: 191.[more]

Li, K., Venter, E., et al.
ANDES: Statistical Tools for the ANalyses of DEep Sequencing

BMC Res Notes. 2010 Jul 15; 3(1): 199.[more]

Eckerle, L. D., Becker, M. M., et al.
Infidelity of SARS-CoV Nsp14-exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing

PLoS Pathog. 2010 May 06; 6(5): e1000896.[more]

Li, K., Brownley, A.
Primer Design for RT-PCR

Methods Mol Biol. 2010 Mar 01; 630: 271-99.[more]

Miller, J. R., Delcher, A. L., et al.
Aggressive Assembly of Pyrosequencing Reads With Mates

Bioinformatics. 2008 Oct 28; 24(24): 2818-24.[more]

Ng, P. C., Levy, S., et al.
Genetic Variation In an Individual Human Exome

PLoS Genet. 2008 Aug 01; 4(8): e1000160.[more]

Li, K., Brownley, A., et al.
Novel Computational Methods for Increasing PCR Primer Design Effectiveness In Directed Sequencing

BMC Bioinformatics. 2008 Apr 11; 9(1): 191.[more]

Rusch, D. B., Halpern, A. L., et al.
The Sorcerer II Global Ocean Sampling Expedition: Northwest Atlantic Through Eastern Tropical Pacific

PLoS Biol. 2007 Mar 13; 5(3): e77.[more]

Goldberg, S. M., Johnson, J., et al.
A Sanger/pyrosequencing Hybrid Approach for the Generation of High-quality Draft Assemblies of Marine Microbial Genomes

Proc Natl Acad Sci U S A. 2006 Jul 13; 103(30): 11240-5.[more]

Rand, V., Huang, J., et al.
Sequence Survey of Receptor Tyrosine Kinases Reveals Mutations In Glioblastomas

Proc Natl Acad Sci U S A. 2005 Oct 04; 102(40): 14344-9.[more]

Mural, R. J., Adams, M. D., et al.
A Comparison of Whole-genome Shotgun-derived Mouse chromosome 16 and the Human Genome

Science. 2002 May 31; 296(5573): 1661-71.[more]