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About

Biographies

Lauren Brinkac
Lead Bioinformatics Analyst

Research Interests and Accomplishments

Lauren Brinkac is a Lead Bioinformatics Analyst in the Informatics Department at the J. Craig Venter Institute (JCVI). Through her work at JCVI, Lauren processed and submitted over 50 prokaryotic genome sequencing projects, and was the lead analyst managing several small and large scale genome projects and submissions. Lauren has extensive experience in structural and functional annotation of genome sequences, comparative genome analysis, and project management. Her research interests include genome annotation, process design and development of annotation pipelines, tool development for genome analysis, and improving microbial gene annotation methods.

Prior to joining JCVI in 2001, Ms. Brinkac managed a team of biologists at The Bode Technology Group, developing forensic methodologies for detecting and identifying trace microbial, plant and human specimens. Ms. Brinkac earned her M.S. in Bioinformatics from George Mason University, and dual B.S. degrees in Biochemistry and Biology from Syracuse University.

Select Publications

Harvill ET, Goodfield LL, et al.
Genome Sequences of Nine Bordetella Holmesii Strains Isolated in the United States.

Genome Announcements. 2014 Jul 01; 2[more]

Dugan VG, Emrich SJ, et al.
Standardized Metadata for Human Pathogen/Vector Genomic Sequences.

PloS One. 2014 Jun 01; 9: e99979.[more]

Lehmann JS, Fouts DE, et al.
Pathogenomic Inference of Virulence-Associated Genes in Leptospira Interrogans.

PLoS Neglected Tropical Diseases. 2013 Oct 01; 7: e2468.[more]

Harvill ET, Goodfield LL, et al.
Genome Sequences of 28 Bordetella pertussis U.S. Outbreak Strains Dating from 2010 to 2012.

Genome Announcements. 2013 Feb 01; 1[more]

Varga JJ, Losada L, et al.
Draft Genome Sequences of Burkholderia cenocepacia ET12 Lineage Strains K56-2 and BC7.

Genome Announcements. 2013 Feb 01; 1[more]

Goll, J., Montgomery, R., et al.
The Protein Naming Utility: a Rules Database for Protein Nomenclature

Nucleic Acids Res. 2010 Jan 01; 38(0): D336-9.[more]

Brinkac, L. M., Davidsen, T., et al.
Pathema: a Clade-specific Bioinformatics Resource Center for Pathogen Research

Nucleic Acids Res. 2009 Oct 20;[more]

Paulsen, I. T., Press, C. M., et al.
Complete Genome Sequence of the Plant Commensal Pseudomonas fluorescens Pf-5

Nat Biotechnol. 2005 Jul 01; 23(7): 873-8.[more]

Haft, D. H., Selengut, J. D., et al.
Genome Properties: a System for the Investigation of Prokaryotic Genetic Content for Microbiology, Genome Annotation and Comparative Genomics

Bioinformatics. 2005 Feb 01; 21(3): 293-306.[more]

Seshadri, R., Adrian, L., et al.
Genome Sequence of the PCE-dechlorinating Bacterium Dehalococcoides ethenogenes

Science. 2005 Jan 07; 307(5706): 105-8.[more]

Moran, M. A., Buchan, A., et al.
Genome Sequence of Silicibacter pomeroyi Reveals Adaptations to the Marine Environment

Nature. 2004 Dec 16; 432(7019): 910-3.[more]

Heidelberg, J. F., Seshadri, R., et al.
The Genome Sequence of the Anaerobic, Sulfate-reducing Bacterium Desulfovibrio vulgaris Hildenborough

Nat Biotechnol. 2004 May 01; 22(5): 554-9.[more]

Methe, B. A., Nelson, K. E., et al.
Genome of Geobacter sulfurreducens : Metal Reduction In Subsurface Environments

Science. 2003 Dec 12; 302(5652): 1967-9.[more]

Read, T. D., Peterson, S. N., et al.
The Genome Sequence of Bacillus anthracis Ames and Comparison to Closely Related Bacteria

Nature. 2003 May 01; 423(6935): 81-6.[more]

Paulsen, I. T., Banerjei, L., et al.
Role of Mobile DNA In the Evolution of Vancomycin-resistant Enterococcus faecalis

Science. 2003 Mar 28; 299(5615): 2071-4.[more]