JCVI: About / Bios / Marcus Jones
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Marcus B. Jones, Ph.D.
Assistant Professor

Research Interests and Accomplishments

Dr. Marcus B. Jones is an Assistant Professor within the Infectious Disease and Genomic Medicine groups at JCVI, where he specializes in a wide variety of gene expression and biomarker discovery studies. His scientific research focuses on employing "omics" technologies to understand various human disease, microbial infection models and the evolution of antibiotic resistance.  He measures changes in human, mouse and bacterial gene expression in various infection models to understand how bacteria cause infections and how the immune system responds to invading microbial pathogens. Dr. Jones also utilizes next generation sequencing technologies to characterize the role of the human microbiome as it relates to human disease.

Dr. Jones received his bachelor's degree at Southern University and A&M College in Baton Rouge, LA in 2000. He received his Ph.D. in Microbiology in 2005 studying in the laboratory of Dr. Martin J. Blaser in The Sackler Institute at New York University School of Medicine. Dr. Jones did his post-doctoral training at The Institute for Genomic Research (TIGR) from 2005-2006 in the laboratory of Dr. Scott N. Peterson in the Pathogen Functional Genomics Resource Center (PFGRC) prior to joining the JCVI. Dr. Jones was the recipient of the UNCF/Merck Graduate Dissertation Fellowship, the David and Lucile Packard Foundation Graduate Fellowship, two-time recipient of the Aspen Health Forum Fellowship and the Keystone Symposium Fellowship. 

Select Publications

Ansong C, Schrimpe-Rutledge AC, et al.
A Multi-omic Systems Approach to Elucidating Yersinia Virulence Mechanisms.

Molecular BioSystems. 2013 Jan 27; 9: 44-54.[more]

Bae D, Liu C, et al.
Global Gene Expression of Listeria monocytogenes to Salt Stress.

Journal of food protection. 2012 May 01; 75: 906-12.[more]

Arpaia, N., Godec, J., et al.
TLR Signaling Is Required for Salmonella typhimurium Virulence

Cell. 2011 Mar 04; 144(5): 675-88.[more]

Boyle-Vavra, S., Jones, M., et al.
Comparative Genome Sequencing of an Isogenic Pair of USA800 Clinical MRSA Isolates Obtained Before and After Daptomycin Treatment Failure

Antimicrob Agents Chemother. 2011 Feb 22;[more]

Festa, R. A., Jones, M. B., et al.
A Novel Copper-responsive Regulon In Mycobacterium tuberculosis

Mol Microbiol. 2011 Jan 11; 79(1): 133-48.[more]

Jones, M. B., Peterson, S. N., et al.
Role of LuxS In Bacillus anthracis Growth and Virulence Factor Expression

Virulence. 2010 Oct 27; 1(2): 72-83.[more]

Safi, H., Fleischmann, R. D., et al.
Allelic Exchange and Mutant Selection Demonstrate That Common Clinical EmbCAB Gene Mutations Only Modestly Increase Resistance to Ethambutol In Mycobacterium tuberculosis

Antimicrob Agents Chemother. 2009 Oct 12;[more]

Pandya, G. A., Holmes, M. H., et al.
Whole Genome Single Nucleotide Polymorphism Based Phylogeny of Francisella tularensis and Its Application to the Development of a Strain Typing Assay

BMC Microbiol. 2009 Oct 07; 9(1): 213.[more]

Perry, J. A., Jones, M. B., et al.
Peptide Alarmone Signalling Triggers an Auto-active Bacteriocin Necessary for Genetic Competence

Mol Microbiol. 2009 Apr 14;[more]

Colangeli, R., Helb, D., et al.
Transcriptional Regulation of Multi-drug Tolerance and Antibiotic-induced Responses by the Histone-like Protein Lsr2 In M. tuberculosis

PLoS Pathog. 2007 Jun 01; 3(6): e87.[more]

Cirz, R. T., Jones, M. B., et al.
Complete and SOS-mediated Response of Staphylococcus aureus to the Antibiotic Ciprofloxacin

J Bacteriol. 2007 Jan 01; 189(2): 531-9.[more]