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About

Biographies

Philip Weyman, Ph.D.
Assistant Professor

Research Interests and Accomplishments

Phil Weyman is an Assistant Professor in the Synthetic Biology and Bioenergy department at JCVI. His research interests focus on developing synthetic biology techniques photosynthetic microorganisms to enhance bioenergy production. Recent research has focused on developing genome editing tools for diatoms, yeast-based DNA assembly methods to clone prokaryotic and eukaryotic chromosomes and engineering cyanobacterial strains with improved hydrogen production capabilities.

Before coming to JCVI, Phil was a postdoctoral researcher at the University of Missouri — St. Louis where he studied hydrogen production in nitrogen fixing cyanobacteria. Phil earned his Ph.D. from the University of California, Davis in Plant Pathology.

Select Publications

Weyman PD, Beeri K, et al.
Inactivation of Phaeodactylum tricornutum Urease Gene Using Transcription Activator-like Effector Nuclease-based Targeted Mutagenesis.

Plant Biotechnology Journal. 2014 Oct 10;[more]

Yonemoto IT, Clarkson BN, et al.
A Broad Survey Reveals Substitution Tolerance of Residues Ligating FeS Clusters in [NiFe] Hydrogenase.

BMC Biochemistry. 2014 Jun 17; 15: 10.[more]

Karas BJ, Jablanovic J, et al.
Transferring Whole Genomes from Bacteria to Yeast Spheroplasts Using Entire Bacterial Cells to Reduce DNA Shearing.

Nature Protocols. 2014 Apr 01; 9: 743-50.[more]

Xu Y, Weyman PD, et al.
Circadian Yin-yang Regulation and Its Manipulation to Globally Reprogram Gene Expression.

Current Biology : CB. 2013 Dec 02; 23: 2365-74.[more]

Karas BJ, Molparia B, et al.
Assembly of Eukaryotic Algal Chromosomes in Yeast.

Journal of Biological Engineering. 2013 Nov 01; 7: 30.[more]

Yonemoto IT, Matteri CW, et al.
Dual Organism Design Cycle Reveals Small Subunit Substitutions That Improve [NiFe] Hydrogenase Hydrogen Evolution.

Journal of Biological Engineering. 2013 Sep 01; 7: 17.[more]

Karas BJ, Jablanovic J, et al.
Direct Transfer of Whole Genomes from Bacteria to Yeast.

Nature Methods. 2013 May 01; 10: 410-2.[more]

Noskov VN, Karas BJ, et al.
Assembly of Large, High G+c Bacterial DNA Fragments In Yeast.

ACS Synthetic Biology. 2012 Jul 20; 1: 267-73.[more]

Vargas, W. A., Weyman, P. D., et al.
[NiFe] Hydrogenase from Alteromonas macleodii With Unusual Stability In the Presence of Oxygen and High Temperature

Appl Environ Microbiol. 2011 Mar 01; 77(6): 1990-8.[more]

Weyman, P. D., Pratte, B., et al.
Hydrogen Production In Nitrogenase Mutants In Anabaena variabilis

FEMS Microbiol Lett. 2011 Mar 01; 304(1): 55-61.[more]

Weyman, P. D., Vargas, W. A., et al.
Heterologous Expression of Alteromonas macleodii and Thiocapsa Roseopersicina [NiFe] Hydrogenases In Escherichia coli

Microbiology. 2011 Feb 24;[more]