JCVI: About / Bios / Rajagopala S. Venkatappa
Section Banner



Rajagopala S. Venkatappa, Ph.D.
Assistant Professor

Research Interests and Accomplishments

Dr. Rajagopala earned a Masters degree in Plant science and Microbiology from Bangalore University, India and a Ph.D. from the University of Heidelberg, Germany in 2006. During his Ph.D. he carried out research on characterizing the protein interaction network of bacterial motility, human herpes viruses, and the Syphilis spirochete Treponema pallidum. Dr. Rajagopala joined The Institute of Genomics Research (TIGR) as a post-doctoral fellow in 2006.

Dr. Rajagopala's major research interest is to use and develop high-throughput technologies to characterize the protein-protein interaction maps (interactome maps). The interactomes are an indispensible tool for systems biology and aid understanding of signaling pathways and biological networks. By using the advanced high throughput yeast-two-hybrid technology, we are carrying out an exhaustive yeast two-hybrid screening to comprehensively describe all protein-protein interactions in E. coli, S. pneumonia and the protein interactions of E. coli and bacteriophage lambda.

Select Publications

Rajagopala, S. V., Hughes, K. T., et al.
Benchmarking Yeast Two-hybrid Systems Using the Interactions of Bacterial Motility Proteins

Proteomics. 2009 Dec 01; 9(23): 5296-302.[more]

Fossum, E., Friedel, C. C., et al.
Evolutionarily Conserved Herpesviral Protein Interaction Networks

PLoS Pathog. 2009 Sep 01; 5(9): e1000570.[more]

Rajagopala, S. V., Uetz, P.
Analysis of Protein-protein Interactions Using Array-based Yeast Two-hybrid Screens

Methods Mol Biol. 2009 May 01; 548: 223-45.[more]

Rajagopala, S. V., Goll, J., et al.
MPI-LIT: a Literature-curated Dataset of Microbial Binary Protein--protein Interactions

Bioinformatics. 2008 Nov 15; 24(22): 2622-7.[more]

Goll, J., Rajagopala, S. V., et al.
MPIDB: The Microbial Protein Interaction Database

Bioinformatics. 2008 Jun 13; 24: 1743-1744.[more]

Titz, B., Rajagopala, S. V., et al.
The Binary Protein Interactome of Treponema Pallidum--the Syphilis Spirochete

PLoS ONE. 2008 May 28; 3(5): e2292.[more]

Rajagopala, S. V., Titz, B., et al.
The Protein Network of Bacterial Motility

Mol Syst Biol. 2007 Mar 01; 3: 128.[more]

Titz, B., Rajagopala, S. V., et al.
Novel Conserved Assembly Factor of the Bacterial Flagellum

J Bacteriol. 2006 Nov 01; 188(21): 7700-6.[more]

Uetz, P., Dong, Y. A., et al.
Herpesviral Protein Networks and Their Interaction With the Human Proteome

Science. 2006 Jan 13; 311(5758): 239-42.[more]