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About

Biographies

Scott Peterson, Ph.D.
Investigator, Scientific Director, PFGRC, Director of Functional Genomics Research and Development

Research Interests and Accomplishments

Dr. Peterson received his undergraduate education at Rutgers University from 1982-1986. Dr. Peterson then pursued a Ph.D. in the laboratory of Dr. Clyde Hutchison at The University of North Carolina at Chapel Hill, where he initiated a characterization of the minimal genome of Mycoplasma genitalium. Dr. Peterson did post-doctoral studies at Glaxo-Wellcome Inc from 1992-1996. Dr. Peterson joined the faculty in 1996 where he has pursued a wide variety of functional and comparative genomics studies.

Dr. Peterson was the co-first author on the global transposon mutagenesis of the M. genitalium genome to define the minimal genetic requirements for life. Dr. Peterson has been using DNA microarrays to conduct gene expression and comparative genomic hybridization studies on a number of bacterial species. More recently, Dr. Peterson has developed novel applications using DNA microarrays to enhance the efficiency of performing functional characterization of microbial genomes. Since 2001, Dr. Peterson has been the Scientific Director of the NIAID's Pathogen Functional Genomics Resource Center (PFGRC). As the scientific leader of the PFGRC, Dr. Peterson has developed additional areas of expertise in functional genomics, particularly focused on high throughput gene cloning and protein expression and proteomics.

Dr. Peterson is interested in the evolution of pathogenic genomes. More recently, Dr. Peterson has developed a number of methods and strategies to enable deeper characterization of metagenomes and has interest in both human and environmental metagenomics. In 2008, Dr. Peterson was promoted to the position of Director of Functional Genomics Research and Development.

Publications

Cirz, R. T., Jones, M. B., et al.
Complete and SOS-mediated response of Staphylococcus aureus to the antibiotic ciprofloxacin
J Bacteriol. 2007 Jan 01; 189(2): 531-9.

Tanaka, M., Earl, A. M., et al.
Analysis of Deinococcus radiodurans's transcriptional response to ionizing radiation and desiccation reveals novel proteins that contribute to extreme radioresistance
Genetics. 2004 Sep 01; 168(1): 21-33.

Peterson, S. N., Sung, C. K., et al.
Identification of competence pheromone responsive genes in Streptococcus pneumoniae by use of DNA microarrays
Mol Microbiol. 2004 Feb 01; 51(4): 1051-1070.

Liu, H., Bergman, N. H., et al.
Formation and composition of the Bacillus anthracis endospore
J Bacteriol. 2004 Jan 01; 186(1): 164-78.

Read, T. D., Peterson, S. N., et al.
The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria
Nature. 2003 May 01; 423(6935): 81-6.

Peterson, S. N., Fraser, C. M.
The complexity of simplicity
Genome Biol. 2001 Feb 08; 2(2): COMMENT2002.

Hutchison, C. A., Peterson, S. N., et al.
Global transposon mutagenesis and a minimal Mycoplasma genome
Science. 1999 Dec 10; 286(5447): 2165-9.

 

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