JCVI: About / Bios / Vladimir Noskov
 
 
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About

Biographies

Vladimir Noskov, Ph.D.
Staff Scientist

Research Interests and Accomplishments

Dr. Noskov is a Staff Scientist in Synthetic Biology and Bioenergy Group at the JCVI, Maryland. He has extensive experience in yeast Saccharomyces cerevisiae genetics, molecular biology, and biochemistry, as well as considerable background in high molecular weight DNA fragment cloning and operating. He is coauthor on a paper describing human synthetic centromere construction.

Currently he is working on developing new methods to enable efficient genetic manipulations of bacterial genomes housed in yeast. He is also doing transformation-associated recombination (TAR)-cloning of natural DNA pieces from bacterial genomes. Prior to joining the JCVI he worked at NIH in the Chromosome Structure and Function Group, where he invented several new applications for the TAR-cloning method. He is the author of 35 publications and 3 invention patents.

Dr. Noskov graduated from St.-Petersburg State University, Russia. He received his Ph.D. from the same university with a specialty in Yeast Genetics. After earning his Ph.D. he spent 5 years in Japan. While there, he studied chromosomal DNA replication and S-phase checkpoint in the yeast Saccharomyces cerevisiae.

Select Publications

Noskov, V. N., Segall-Shapiro, T. H., et al.
Tandem Repeat Coupled With Endonuclease Cleavage (TREC): a Seamless Modification Tool for Genome Engineering In Yeast

Nucleic Acids Res. 2010 May 08; 38(8): 2570-6.[more]

Benders, G. A., Noskov, V. N., et al.
Cloning Whole Bacterial Genomes In Yeast

Nucleic Acids Res. 2010 Mar 07; 38(8): 2558-69.[more]

Lartigue, C., Vashee, S., et al.
Creating Bacterial Strains from Genomes That Have Been Cloned and Engineered In Yeast

Science. 2009 Aug 20;[more]

Kim, J. H., Ebersole, T., et al.
Human Gamma-satellite DNA Maintains Open Chromatin Structure and Protects a Transgene from Epigenetic Silencing

Genome Res. 2009 Apr 01; 19(4): 533-44.[more]

Nakano, M., Cardinale, S., et al.
Inactivation of a Human Kinetochore by Specific Targeting of Chromatin Modifiers

Dev Cell. 2008 Apr 01; 14(4): 507-22.[more]

Gibson, D. G., Benders, G. A., et al.
Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

Science. 2008 Jan 24; 319(5867): 1215-20.[more]