JCVI: A New Transformation-deficient Mutant of Haemophilus influenzae Rd With Normal DNA Uptake
 
 
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Gwinn, M. L., Ramanathan, R., Smith, H. O., Tomb, J. F.

A New Transformation-deficient Mutant of Haemophilus influenzae Rd With Normal DNA Uptake

J Bacteriol. 1998 Feb 01; 180(3): 746-8.

PubMed Citation

Abstract

Haemophilus influenzae Rd is a gram-negative natural transformer. A mutant strain, RJ248, that has normal DNA uptake and translocation but whose transformation frequency is 300 times lower than that of wild-type H. influenzae and whose phage recombination is 8 times lower was isolated. The affected gene, comM, is induced during competence development in wild-type H. influenzae but not in RJ248.