JCVI: Biological Activities and Corresponding SARs of Andrographolide and Its Derivatives.
 
 
Section Banner

Publications

Citation

Zhou B, Zhang D, Wu X

Biological Activities and Corresponding SARs of Andrographolide and Its Derivatives.

Mini Reviews In Medicinal Chemistry. 2013 Feb 01; 13: 298-309.

External Citation

Abstract

In recent years, pharmaceutical chemists have synthesized large numbers of andrographolide derivatives, which bear important biological activities such as anti-inflammatory, antibacterial, antivirus, antitumor, antidiabetic, and antifeedant. Consequently, corresponding SARs were increasingly obvious. This paper aimed to review all the available literature in this field, highlighting the significant achievements on the structural modification and SARs of andrographolide and its derivatives.