Ghedin, E., Wang, S. L., Foster, J. M., Slatko, B. E.
First Sequenced Genome of a Parasitic Nematode
Trends in Parasitology. 2004 Apr 01; 20(4): 151-153.
The genome of the human filarial parasite, Brugia malayi, has been sequenced at ninefold redundancy using a whole-genome shotgun approach. This represents the first parasitic nematode genome to be decoded, and the data generated allows comparative analyses at the whole-genome scale with two Caenorhabditis free-living nematodes. An update on the current status and advances of the B. malayi project is presented.