JCVI: Genetic Variants in the MTOR Pathway and Interaction With Body Size and Weight Gain on Breast Cancer Risk in African-American and European American Women.
 
 
Section Banner

Publications

Citation

Cheng TD, Shankar J, Zirpoli G, Roberts MR, Hong CC, Bandera EV, Ambrosone CB, Yao S

Genetic Variants in the MTOR Pathway and Interaction With Body Size and Weight Gain on Breast Cancer Risk in African-American and European American Women.

Cancer Causes & Control : CCC. 2016 Jun 17;

External Citation

Abstract

Positive energy imbalance and growth factors linked to obesity promote the phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (mTOR) pathway. As the obesity-breast cancer associations differ between European American (EA) and African-American (AA) women, we investigated genetic variants in the mTOR pathway and breast cancer risk in these two racial groups.