Brown, D. R., Farmerie, W. G., May, M., Benders, G. A., Durkin, A. S., Hlavinka, K., Hostetler, J., Jackson, J., Johnson, J., Miller, R. H., Paralanov, V., Radune, D., Szczypinski, B., Glass, J. I.
Genome Sequences of Mycoplasma alligatoris A21JP2T and Mycoplasma crocodyli MP145T
J Bacteriol. 2011 Apr 01;
Mycoplasma alligatoris and Mycoplasma crocodyli are closely-related siblings, one being highly virulent and the other relatively attenuated. We compared their genomes to better understand the mechanisms and origins of M. alligatoris' remarkable virulence amid a clade of harmless or much lower-virulence species. Although its chromosome was refractory to closure, M. alligatoris differed most notably by its complement of sialidases and other genes of the N-acetylneuraminate scavenging and catabolism pathway.