JCVI: The Transmission Dynamics and Diversity of Human Metapneumovirus in Peru.
 
 
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Citation

Pollett S, Trovão NS, Tan Y, Eden JS, Halpin RA, Bera J, Das SR, Wentworth D, Ocaña V, Mendocilla SM, Álvarez C, Calisto ME, Garcia J, Halsey E, Ampuero JS, Nelson MI, Leguia M

The Transmission Dynamics and Diversity of Human Metapneumovirus in Peru.

Influenza and Other Respiratory Viruses. 2017 Dec 29;.

External Citation

Abstract

The transmission dynamics of human metapneumovirus (HMPV) in tropical countries remain unclear. We examined the spatial patterns of HMPV in three ecologically diverse Peruvian locales (Lima, Iquitos and Piura) through phylogenetic analysis of 61 complete genomes, which revealed extensive genetic diversity generated by frequent viral introductions, with little evidence of local persistence. While considerable viral traffic between non-Peruvian countries and Peru was observed, HMPV epidemics in Peruvian locales were more frequently epidemiologically linked with other sites within Peru. Greater diversity of HMPV in Iquitos compared to Piura may relate to higher volumes of human movement, including air traffic to this location. This article is protected by copyright. All rights reserved.