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Genomic Medicine

Overview

The first sequencing of the human genome in 2000 by Dr. Venter and colleagues provided a glimpse of humans at our most basic molecular level. JCVI's most recent publication of the first diploid human genome — the genome of one individual in which both sets of inherited chromosomes were presented, represents a major step forward in the enablement of individualized genomic medicine and in enhanced understanding of human biology.

The Genomic Medicine Group at JCVI has been at the forefront of human genomics research and they continue their focus on providing a better molecular understanding of human health and disease propensity by further study of this first diploid human genome. The team is setting the stage for more individual genomes to be sequenced and analyzed over the next decade since a deep understanding of disease will only be possible by having many sequenced genomes available for comparison.

The team is also working in collaboration with several groups to better understand the genomic basis for some of the most prevalent and vexing diseases such as cancer and diseases of the heart, lungs, and blood.

Featured Highlights

A Protein-Protein Interaction Map of E. coli

A yeast two-hybrid screen will help us to discover all protein-protein interactions in E. coli, an important pathogen and model organism.

Animal Microbiome Studies (AMS)

Animal Microbiome Sciences focuses on studying the microbial populations that natively inhabit these animals, allowing us determine their...

Genome-wide prediction and analysis of coding variants

We are developing methods to discover genetic variants associated with disease — an important step toward personalized medicine.

Human Diploid Genome

The first publication of a diploid human genome from one person: A step closer to truly individualized genomic medicine.

Human Microbiome Project (HMP)

The NIH Human Microbiome Project (HMP) was initiated to help determine the core human microbiome, to understand the changes in the human...

Human Microbiome Studies (HMS)

As a leading genomics research organization, the J. Craig Venter Institute has numerous projects and programs that are focused on this...

Single Cell Genomics of Human Microbial Flora

We are developing methods using single cell genomics & MDA to obtain bacterial genomes from human specimens to discover their roles in...

Southern African Genome Diversity Study

Research Team led by JCVI Scientists Uncover More Complexity and Detail in Southern African Genomic Diversity.

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