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Infectious Disease

Overview

As the population on our planet continues to increase, and as issues like global climate change arise, the threat of emerging infectious diseases intensifies. One of the longstanding research focus areas at the JCVI is microbial and viral genomics and how those relate to human infectious disease. That work continues today in several major areas including: comparative microbial genomics in sexually transmitted pathogens, elucidation of human microbial flora within various body cavities, sequencing and analysis of human pathogens such as anthrax and the mosquito species that carry yellow fever and malaria, and various strains of influenza and coronavirus. Having a thorough genomic understanding of these diseases is already enabling JCVI researchers to collaborate on new vaccines and treatments for these worldwide health threats.

Featured Highlights

Bioinformatics Resource Center (BRC)

Pathema: A Clade Specific NIAID BRC designed to support bio-defense and infectious disease research.

Center for Structural Genomics of Infectious Disease (CSGID)

The Center's mission is to solve the three-dimensional structure of proteins from pathogens in the NIAID Category A-C priority lists and org...

Microbial Sequencing Center (MSC)

The JCVI Microbial Sequence Center (MSC), sponsored by the National Institute for Allergies and Infectious Disease (NIAID), addresses the sc...

Pathogen Functional Genomics Resource Center (PFGRC)

The PFGRC is a centralized facility providing the research community with resources necessary to conduct functional genomics research on hum...

Quorum sensing in pathogenic Burkholderias

Burkholderia pseudomallei is a prevalent environmental pathogen in tropical areas of the world, particularly in Southeast Asia and Northern ...

Whole genome sequencing of the soil fungus R. solani AG-3

Rhizoctonia solani anastomosis group 3 (AG-3) is a common fungal inhabitant of the soil ecosystem and has a worldwide distribution.