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The Microbial Protein Interaction Database

Interaction Evidences

HP_0392 - cheY ( Helicobacter pylori (Campylobacter pylori) )

Protein A	Protein B
O25153 Histidine kinase (CheA) HP_0392	P71403 Chemotaxis protein cheY homolog cheY HP_1067
CMR Search...	CMR Search...
GO MF: two-component sensor activity GO MF: ATP binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: chemotaxis GO BP: regulation of transcription, DNA-dependent GO BP: peptidyl-histidine phosphorylation GO BP: two-component signal transduction system (p...	GO MF: magnesium ion binding GO MF: two-component response regulator activity GO CC: cytoplasm GO BP: ciliary or flagellar motility GO BP: chemotaxis GO BP: regulation of transcription, DNA-dependent GO BP: two-component signal transduction system (p...

List of evidences (121)

Experiments (1)

Method

DB Source

Type

Publication

two hybrid

physical association

Rain JC et al. (2001)

Interologs (118)

cheA (61%) - cbrR (31%) (Campylobacter jejuni)

Geometric mean of BLAST Identity: 44% Positives: 61% E-Value: 0

Method	DB Source	Type	Publication
two hybrid		physical association	Parrish JR et al. (2007)
two hybrid array		physical association	Parrish JR et al. (2007)

cheA (19%) - cheY (48%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 30% Positives: 44% E-Value: 5.97e-52

Method	DB Source	Type	Publication
biochemical		physical association	Stewart RC et al. (2004)
cosedimentation in solution		physical association	Kott L et al. (2004)
enzymatic study		physical association	Schuster M et al. (2001)
experimental interaction detection		physical association	Mayover TL et al. (1999)
fluorescence technology		physical association	Stewart RC et al. (2004)
two hybrid array		physical association	Rajagopala SV et al. (2009)

cheA (22%) - cheY (38%) (Thermotoga maritima)

Geometric mean of BLAST Identity: 29% Positives: 44% E-Value: 1.28e-54

Method

DB Source

Type

Publication

x-ray crystallography

direct interaction

Park SY et al. (2004)

cheA (23%) - cheY (35%) (Treponema denticola)

Geometric mean of BLAST Identity: 28% Positives: 42% E-Value: 1.13e-50

Method

DB Source

Type

Publication

two hybrid

physical association

Sim JH et al. (2005)

cheA (17%) - cheY2 (35%) (Rhizobium meliloti (Sinorhizobium meliloti))

Geometric mean of BLAST Identity: 25% Positives: 41% E-Value: 4.01e-40

Method	DB Source	Type	Publication
fluorescence microscopy		physical association	Riepl H et al. (2008)

difE (17%) - difD (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 40% E-Value: 4.59e-36

Method

DB Source

Type

Publication

two hybrid

physical association

Lancero HL et al. (2005)

difE (17%) - nla19 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 23% Positives: 36% E-Value: 1.34e-35

Method

DB Source

Type

Publication

two hybrid

physical association

Lancero HL et al. (2005)

cheA (19%) - cheB (24%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 22% Positives: 37% E-Value: 3.17e-41

Method	DB Source	Type	Publication
affinity chromatography technology		direct interaction	Yamamoto K et al. (2005)
biochemical		physical association	Yamamoto K et al. (2005)
biochemical		physical association	Tawa P et al. (1994)
cosedimentation		physical association	Kott L et al. (2004)
two hybrid array		physical association	Rajagopala SV et al. (2009)

slr2098 (11%) - slr2100 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 15% Positives: 30% E-Value: 5.65e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (5%) - cheY (48%) (Escherichia coli O157:H7 - Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 15% Positives: 24% E-Value: 1.03e-19

Method	DB Source	Type	Publication
x-ray crystallography		physical association	Kato M et al. (1999)

cheB (4%) - cheY (48%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 14% Positives: 22% E-Value: 3.30e-18

Method	DB Source	Type	Publication
unspecified method		physical association	Ninfa EG et al. (1991)

MXAN_2785 (5%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 2.08e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (5%) - MXAN_3450 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 23% E-Value: 8.43e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 20% E-Value: 1.14e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (31%) - MXAN_4164 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 22% E-Value: 3.10e-12

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (5%) - MXAN_4164 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 13% Positives: 24% E-Value: 5.65e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1759 (5%) - slr1760 (31%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 9.32e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2100 (5%) - slr2098 (29%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 3.31e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

arcB (5%) - hnr (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 2.54e-10

Method	DB Source	Type	Publication
enzymatic study		physical association	Mika F et al. (2005)

MXAN_7396 (4%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 6.04e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

cheB1 (5%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 2.71e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_6149 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 1.76e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - MXAN_6149 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 6.04e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 2.08e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_6149 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 20% E-Value: 6.04e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (5%) - asgD (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 6.91e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (5%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 3.20e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (5%) - MXAN_7396 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 23% E-Value: 2.37e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2785 (5%) - MXAN_4645 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 4.63e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (5%) - MXAN_4072 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 3.92e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2785 (25%) - MXAN_2785 (5%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 4.48e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (4%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 19% E-Value: 2.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.76e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_7396 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.30e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_1680 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 1.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (4%) - MXAN_5313 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 21% E-Value: 3.42e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_5313 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 12% Positives: 22% E-Value: 3.00e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

slr1759 (5%) - slr1594 (27%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 8.16e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (4%) - slr2104 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 5.65e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1905 (5%) - slr1305 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.70e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1305 (4%) - sll1905 (27%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.30e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

cpxR (30%) - cpxR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 7.63e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (4%) - ompR (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.34e-11

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

phoB (28%) - phoB (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 4.62e-12

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

arcA (28%) - arcA (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 9.64e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

glnG (27%) - glnG (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 6.46e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Salinas P et al. (2003)

baeR (24%) - baeR (5%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 8.43e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (29%) - cusR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 3.20e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

yedW (4%) - cusR (29%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.44e-09

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

asgD (4%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 23% E-Value: 3.20e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 22% E-Value: 4.78e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - asgD (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 2.01e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - MXAN_7396 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 23% E-Value: 2.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (5%) - asgD (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 9.02e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (5%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 4.19e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

cheB1 (5%) - MXAN_7396 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 3.10e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP3 (5%) - asgD (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 5.85e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - nla28 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 2.62e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 4.05e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_3450 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 2.45e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_3450 (30%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.64e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_6149 (32%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 1.18e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - asgD (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 6.91e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 3.20e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_7396 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 2.37e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - pilR (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 1.03e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - pilR (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 3.54e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - pilR (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 5.29e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - pilR (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 6.91e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_7206 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 8.16e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_4645 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 6.91e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_1349 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.88e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

phoP2 (5%) - MXAN_4072 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 3.92e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5995 (5%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 20% E-Value: 6.68e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4164 (5%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 2.45e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_4164 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.64e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_4164 (31%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.10e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (4%) - pilR (28%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 19% E-Value: 6.25e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_5313 (33%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 11% Positives: 21% E-Value: 1.18e-11

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - frzZ (23%) (Myxococcus xanthus (strain DK 1622) - Myxococcus xanthus)

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 8.73e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

TP_0519 (27%) - TP_0519 (4%) (Treponema pallidum)

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.18e-07

Method

DB Source

Type

Publication

two hybrid array

physical association

Titz B et al. (2008)

cheY (4%) - cheB (24%) (Salmonella typhimurium)

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.39e-08

Method	DB Source	Type	Publication
unspecified method		physical association	Ninfa EG et al. (1991)

sll1228 (4%) - sll1229 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 8.43e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

sll1229 (4%) - sll1228 (28%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 4.19e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1594 (4%) - slr1759 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 1.54e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1594 (27%) - slr1594 (4%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 2.08e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2104 (4%) - slr1305 (23%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 1.30e-10

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr2024 (25%) - slr2024 (4%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 7.89e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

slr1760 (4%) - slr1759 (25%) (Synechocystis sp (strain PCC 6803))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 2.22e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Sato S et al. (2007)

phoP (27%) - phoP (4%) (Bacillus subtilis)

Geometric mean of BLAST Identity: 10% Positives: 22% E-Value: 2.62e-11

Method	DB Source	Type	Publication
genetic interference		physical association	Chen Y et al. (2003)
x-ray crystallography		physical association	Chen Y et al. (2003)

yedW (24%) - yedW (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 1.59e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (29%) - ompR (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 4.94e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

ompR (4%) - phoB (28%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 22% E-Value: 1.70e-10

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

qseB (25%) - qseB (4%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 7.64e-07

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

cusR (4%) - yedW (24%) (Escherichia coli (strain K12))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 3.54e-08

Method	DB Source	Type	Publication
fluorescent resonance energy transfer		physical association	Gao R et al. (2008)

MXAN_2606 (4%) - asgD (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 1.35e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (26%) - MXAN_2606 (4%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 6.25e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 9.32e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_7396 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 4.63e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - cheB1 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.30e-06

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - cheB1 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 4.48e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - cheB1 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 8.73e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

asgD (4%) - phoP3 (23%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 2.30e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - asgD (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 2.71e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 1.26e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_7396 (27%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 9.32e-09

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_4645 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 1.35e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (4%) - MXAN_4645 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 21% E-Value: 4.63e-08

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_4645 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 9.02e-08

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_4072 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 7.64e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7396 (4%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.30e-06

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

asgD (4%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 4.48e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_4645 (4%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 1.76e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_2606 (4%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 8.73e-07

Method

DB Source

Type

Publication

two hybrid

physical association

Whitworth DE et al. (2008)

MXAN_7363 (4%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 20% E-Value: 3.66e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_7363 (4%) - MXAN_2785 (25%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 18% E-Value: 5.12e-07

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_5313 (4%) - MXAN_4645 (24%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 10% Positives: 19% E-Value: 8.16e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

MXAN_1349 (3%) - MXAN_2606 (26%) (Myxococcus xanthus (strain DK 1622))

Geometric mean of BLAST Identity: 9% Positives: 21% E-Value: 7.14e-09

Method	DB Source	Type	Publication
two hybrid		physical association	Whitworth DE et al. (2008)

Domain-Domain Interactions (2)

Method	DB Source	Type	Domain A	Domain B
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Response_reg
structural domain contact	3DID,iPfam	predicted interaction	Response_reg	Hpt

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